Diisopropyl Succinate

Diisopropyl succinate is a colorless to pale yellow, transparent liquid with a very faint, mild, ester-like aroma—lacking the pungent, fruity scent characteristic of lower-molecular-weight monoesters. It is insoluble in water but miscible with ethanol, diethyl ether, acetone, ethyl acetate, toluene, and hydrocarbons; it exhibits good solvency for nitrocellulose and acrylic resins.

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Product Introduction

Zouping Jinxing Chemical Co., Ltd. is one of the leading manufacturers and suppliers of diisopropyl succinate in China. If you're going to wholesale bulk diisopropyl succinate made in China, welcome to get free sample from our factory. All customized products are with high quality and low price.

Basic physical properties

CAS: 141-60-6 (Commonly known as diisopropyl succinate)
Appearance: Colorless, transparent liquid at room temperature (may become slightly cloudy at low temperatures but does not crystallize like the dimethyl ester)
Boiling point: Approx. 208–210°C (atmospheric pressure), 120–125°C / 1.3 kPa
Melting point: <–20°C (does not crystallize; facilitates low-temperature handling)
Density: 1.020–1.030 g/cm³ (20°C); lighter than the dimethyl ester (1.12) but still heavier than monoesters
Refractive index: n²⁰ᴅ ≈ 1.420
Solubility: Insoluble in water (<0.1 g/100 mL); miscible with ethanol, diethyl ether, acetone, ethyl acetate, toluene, and hydrocarbons; exhibits good solvency for nitrocellulose and acrylic resins
Flash point: Approx. 96°C (closed cup); combustible liquid (Category 4); superior safety profile compared to the vast majority of monoesters
Vapor pressure: Extremely low at 20°C (<0.05 kPa); virtually non-volatile

Primary Uses

High-boiling inert solvent/plasticizer precursor: For coatings, electronic adhesives, and specialty inks; characterized by low volatility and low migration.
Organic synthesis intermediate: Precursor for succinic acid-based pharmaceuticals (e.g., succinate derivatives), pesticides, and fragrances.
Bio-based route: Produced via the esterification of fermentation-derived succinic acid with acetone (or isopropanol); classified as a "bio-based diester."
Chromatographic standard and analytical reference material.

Safety and Physiology

Toxicity:Diisopropyl Succinate is low toxicity. Oral LD₅₀ in rats ≈ 3.0–4.0 g/kg (estimated value; no data indicating high toxicity); mildly irritating to skin and mucous membranes; non-accumulative.
Ecology: Biodegradable; low aquatic toxicity.
Storage and Transport: Store in a cool, dry place; avoid exposure to strong acids, strong bases, and heat (to prevent isopropyl elimination); Class 3, PG III, or managed as a combustible liquid.