Dimethyl Succinate

Dimethyl succinate—also known as dimethyl butanedioate—appears as colorless, transparent crystals or a colorless liquid at low temperatures (existing in a state between solid and liquid at room temperature, around 20°C). It lacks a strong fruity aroma, possessing instead a very faint, slightly sweet, ester-like scent; it is a lower-molecular-weight and readily available type of dicarboxylic acid diester.

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Product Introduction

Zouping Jinxing Chemical Co., Ltd. is one of the leading manufacturers and suppliers of dimethyl succinate in China. If you're going to wholesale bulk dimethyl succinate made in China, welcome to get free sample from our factory. All customized products are with high quality and low price.

Basic physical properties

CAS: 106-65-0
Appearance: Dimethyl Succinate is colorless orthorhombic crystals at room temperature; colorless, transparent liquid when molten
Melting point: 19–20°C (may crystallize at room temperature in winter/spring; liquid in summer)
Boiling point: 196–197°C (atmospheric pressure), 108–110°C / 1.6 kPa
Density: 1.117–1.120 g/cm³ (20°C, liquid); significantly denser than monoesters (due to the presence of two ester groups)
Refractive index: n²⁰ᴅ ≈ 1.422 (liquid)
Solubility: Slightly soluble in water (approx. 1.5 g/100 mL at 20°C); miscible with ethanol, diethyl ether, acetone, and ethyl acetate; readily soluble in chloroform and benzene
Flash point: 88–90°C (closed cup); combustible liquid (Category 4); good safety profile
Vapor pressure: Very low at 20°C (<0.1 kPa)

Primary Uses

Organic synthesis intermediate: Dimethyl Succinate is used for the production produce succinylated compounds, pharmaceuticals (e.g., side chains for certain antihypertensive drugs), pesticides, and fragrance precursors.
Green solvent/additive: High boiling point and low volatility; used in coatings and electronics cleaning applications.
Bio-based platform chemical: Produced via the esterification of succinic acid (derived from fermentation) with methanol; classified as a "bio-based diester."
Analytical standard: Reference material for GC/MS retention indices.

Safety and Physiology

Toxicity:Dimethyl Succinate is low toxicity. Oral LD₅₀ in rats ≈ 3.2 g/kg; causes mild irritation to skin and mucous membranes; no significant cumulative toxicity.
Ecology: Biodegradable; low aquatic toxicity.
Storage and Transport: Store in a cool, dry place; protect from moisture (prone to hygroscopic caking); store separately from strong bases.