Trichlorosilane

A: Rat oral LD₅₀ is approximately 1030 mg/kg; inhalation LC₅₀ (mouse, 2h) is 1.5–2 mg/L-moderately toxic via oral ingestion, but highly irritating via inhalation; Vapors cause severe eye and respiratory tract burns and (delayed) pulmonary edema; liquid causes deep, necrotic skin ulcers; Reference maximum allowable concentration in Chinese workplaces is 3 mg/m³ (stricter than the HCl analogy); ACGIH sets a Ceiling limit of 2 ppm (calculated as HCl); Not classified as a carcinogen by IARC, though long-term exposure to HCl causes dental erosion and chronic bronchitis; GHS Label: Danger; H224 (Extremely flammable) + H250 (Pyrophoric in air) + H302/H332 (Harmful if swallowed/inhaled) + H314 (Causes severe skin burns and eye damage) + H331 (Toxic if inhaled) + H260 (In contact with water releases flammable gases).

A: Fully enclosed stainless steel system + N₂/He purge + leak alarm (HCl/flammable); open glass containers are prohibited. Store cylinders in a dry, explosion-proof gas cylinder room (≤25°C); secure upright and maintain residual pressure to prevent back-suck; keep isolated (≥50 m) from water, alkalis, alcohols, amines, oxidizers, and food. PPE: Level A chemical-resistant suit + SCBA for leak handling; full-face respirator + acid-resistant gloves (butyl rubber) + flame-retardant chemical-resistant suit for routine inspections; bare hands strictly prohibited. Firefighting: Dry powder, CO₂, dry sand, or dry stone powder-water and foam are strictly prohibited (reaction releases HCl and H₂, posing an ignition risk); use water mist to cool the cylinder exterior during a fire, avoiding direct spraying of the liquid contents. Absorb leaks with dry sand, vermiculite, or cement; neutralize exhaust HCl via remote spraying with alkaline solution (limewater/soda solution); prevent entry into sewers.