Methyl P-toluate

Methyl p-toluate is a white to pale yellow crystalline solid at room temperature and a colorless liquid when melted; it is insoluble in water but soluble in methanol, ethanol, diethyl ether, acetone, ethyl acetate, aromatic hydrocarbons (such as S-100), and dichloromethane; it possesses partial solvency for resins.

Send Inquiry

Product Introduction

Zouping Jinxing Chemical Co., Ltd. is one of the leading manufacturers and suppliers of methyl p-toluate in China. If you're going to wholesale bulk methyl p-toluate made in China, welcome to get free sample from our factory. All customized products are with high quality and low price.

Basic physical properties

Appearance:Methyl P-toluate is white to pale yellow crystalline solid at room temperature (high-purity grade appears as colorless needle-like crystals); colorless liquid when melted by heat.
Melting point: 33–35°C (some literature cites 34–36°C; exists as a solid near room temperature).
Boiling point: 217–219°C (atmospheric pressure); 95–98°C/10 mmHg (reduced pressure).
Density: 1.067 g/cm³ (20°C; denser than water in liquid state).
Refractive index: n²⁰_D approx. 1.517 (measured in liquid state).
Flash point: 91–93°C (closed cup); combustible solid/high-flash-point liquid (not classified as low-flash-point).
Vapor pressure: Approx. 0.08 mmHg (25°C); slow evaporation at room temperature.
Solubility: Insoluble in water (<0.1 g/L); soluble in methanol, ethanol, diethyl ether, acetone, ethyl acetate, aromatic hydrocarbons (e.g., S-100), and dichloromethane; exhibits partial solvency for resins.

Primary Uses

Pharmaceutical/Agrochemical Intermediates: Synthesis of *p*-methylbenzoyl compounds, ibuprofen side-chain analogs, and herbicide intermediates
Organic Synthetic Building Blocks: Suzuki coupling (bromination followed by coupling), ester hydrolysis to carboxylic acids, and methyl oxidation to terephthalic acid derivatives
Fragrances/Fine Chemicals: Limited use as a fixative in soap fragrances (subtle scent; not a primary fragrance note)
Analytical Standards: GC/MS calibration and reference standards for pharmaceutical impurities

Safety and Toxicology

GHS: H315 (Skin irritation) / H319 (Eye irritation) / H335 (Respiratory irritation); Signal word: Warning
Acute toxicity:Methyl P-toluate is low to moderate; oral LD₅₀ in rats is approximately in the 2000–4000 mg/kg range (estimated; no classification for high toxicity)
Exposure: Crystalline dust irritates eyes and nose; liquid irritates skin; handle as a combustible, irritating chemical
Protection: Work in a fume hood; wear safety goggles, nitrile gloves, and a lab coat; avoid inhaling dust or vapors
Storage and transport: Store in a cool, sealed container (prevent melting/leakage above 35°C); keep separate from strong bases and strong oxidizing agents; not listed under Class 6.1; handle as a general combustible organic solid